Resin filler composition for purifying human plasminogen and application thereof
The invention relates to a resin filler composition for purifying human plasminogen and application thereof. The resin comprises: (1) an anion exchange resin filler, which has a base frame of polyacrylate, a functional group of CH2N + (CH3) 3, a particle size of 70-90 [mu] m, a pressure resistance of 5 bar, a working pH range of 2-12, a stable chemical structure in solutions of methanol, ethanol, isopropanol and the like, and a tolerable temperature range of 4-30 DEG C; (2) affinity chromatography resin filler: 1) affinity chromatography resin filler with polyacrylate as a base frame, RNH (C7H12) COOH as a functional group, a particle size of about 80 [mu] m and a withstand pressure of 5 bar; or 2) an affinity chromatography resin filler with a base frame of porous cross-linked 6% agarose, a functional group of RNHCHOOH (CH2) 4NH2, a particle size of about 90 [mu] m, a withstand voltage of 3 bar and a working pH range of 2-12; and (3) cation exchange resin filler, wherein a base frame of the cation exchange resin filler is polyacrylate, and a functional group of the cation exchange resin filler is (CH3) 3SO3..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 25. Aug. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
ZHOU YANXIANG [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-08-25, Last update posted on www.tib.eu: 2023-12-05, Last updated: 2023-12-08 |
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| Patentnummer: |
CN116640748 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA018533876 |
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| 520 | |a The invention relates to a resin filler composition for purifying human plasminogen and application thereof. The resin comprises: (1) an anion exchange resin filler, which has a base frame of polyacrylate, a functional group of CH2N + (CH3) 3, a particle size of 70-90 [mu] m, a pressure resistance of 5 bar, a working pH range of 2-12, a stable chemical structure in solutions of methanol, ethanol, isopropanol and the like, and a tolerable temperature range of 4-30 DEG C; (2) affinity chromatography resin filler: 1) affinity chromatography resin filler with polyacrylate as a base frame, RNH (C7H12) COOH as a functional group, a particle size of about 80 [mu] m and a withstand pressure of 5 bar; or 2) an affinity chromatography resin filler with a base frame of porous cross-linked 6% agarose, a functional group of RNHCHOOH (CH2) 4NH2, a particle size of about 90 [mu] m, a withstand voltage of 3 bar and a working pH range of 2-12; and (3) cation exchange resin filler, wherein a base frame of the cation exchange resin filler is polyacrylate, and a functional group of the cation exchange resin filler is (CH3) 3SO3. | ||
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| 650 | 4 | |a C12N: Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media (microbiological testing media c12q0001000000) | |
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