Nano-drug for adenosine receptor with open blood-brain barrier, preparation method of nano-drug, and application of nano-drug in resisting nerve toxic agent poisoning
The invention belongs to the field of medicines, and particularly relates to a nano-drug for treating cerebral diseases, in particular to a related drug for treating acute cerebral poisoning. The medicine is prepared by loading an acetylcholin esterase heavy activator on spherical nanoparticles formed by phosphatidylserine and supplementing an adenosine receptor stimulant. The compound can effectively penetrate through the blood brain barrier to rapidly release drugs to the central nervous system, is high in reactivation rate of acetylcholin esterase, is simple and convenient to prepare, and can be used for rapidly treating organophosphorus compound poisoning of the central nervous system. The invention also relates to a preparation method and application of the nano-drug..
Medienart: |
Patent |
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Erscheinungsjahr: |
2023 |
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Erschienen: |
2023 |
Enthalten in: |
Europäisches Patentamt - (2023) vom: 01. Aug. Zur Gesamtaufnahme - year:2023 |
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Sprache: |
Englisch |
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Beteiligte Personen: |
WANG YONGAN [VerfasserIn] |
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Links: |
Volltext [kostenfrei] |
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Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-08-01, Last update posted on www.tib.eu: 2023-12-05, Last updated: 2023-12-08 |
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Patentnummer: |
CN116509817 |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
EPA018449522 |
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520 | |a The invention belongs to the field of medicines, and particularly relates to a nano-drug for treating cerebral diseases, in particular to a related drug for treating acute cerebral poisoning. The medicine is prepared by loading an acetylcholin esterase heavy activator on spherical nanoparticles formed by phosphatidylserine and supplementing an adenosine receptor stimulant. The compound can effectively penetrate through the blood brain barrier to rapidly release drugs to the central nervous system, is high in reactivation rate of acetylcholin esterase, is simple and convenient to prepare, and can be used for rapidly treating organophosphorus compound poisoning of the central nervous system. The invention also relates to a preparation method and application of the nano-drug. | ||
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