PREPARATION METHOD AND APPLICATION OF ZINC HYALURONATE
The present application provides a preparation method for zinc hyaluronate, comprising the following steps: adding sodium hyaluronate into an acidic water-containing organic medium that contains a zinc salt, and carrying out primary replacement to obtain a zinc hyaluronate precipitate; washing the precipitate using a washing liquid; dehydrating the washed precipitate using a dehydration liquid and drying same to obtain a zinc hyaluronate powder. The present application optimizes, on the basis of a solid replacement method, the zinc salt concentration in the replacement liquid, the replacement liquid volume, the replacement time, and the number of replacements, and solves the problems of numerous replacements, long time, large molecular weight consumption, and low zinc salt utilization rate in existing zinc hyaluronate production processes. The production cycle is greatly shortened, the replacement efficiency is improved, the contact time between the raw materials and the acidic replacement liquid is reduced, and the molecular weight of the product is prevented from being greatly lowered. The present application provides a method for rapidly and efficiently producing zinc hyaluronate, which is suitable for large-scale production of zinc hyaluronate..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 26. Okt. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
FENG NING [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Sonstige Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-10-26, Last update posted on www.tib.eu: 2023-11-30, Last updated: 2023-12-08 |
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| Patentnummer: |
WO2023202613 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA018417302 |
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| 520 | |a The present application provides a preparation method for zinc hyaluronate, comprising the following steps: adding sodium hyaluronate into an acidic water-containing organic medium that contains a zinc salt, and carrying out primary replacement to obtain a zinc hyaluronate precipitate; washing the precipitate using a washing liquid; dehydrating the washed precipitate using a dehydration liquid and drying same to obtain a zinc hyaluronate powder. The present application optimizes, on the basis of a solid replacement method, the zinc salt concentration in the replacement liquid, the replacement liquid volume, the replacement time, and the number of replacements, and solves the problems of numerous replacements, long time, large molecular weight consumption, and low zinc salt utilization rate in existing zinc hyaluronate production processes. The production cycle is greatly shortened, the replacement efficiency is improved, the contact time between the raw materials and the acidic replacement liquid is reduced, and the molecular weight of the product is prevented from being greatly lowered. The present application provides a method for rapidly and efficiently producing zinc hyaluronate, which is suitable for large-scale production of zinc hyaluronate. | ||
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