METHODS OF USING PLANAR OR DEFOCUSED ACOUSTIC WAVES FOR NON-INVASIVE SONODYNAMIC THERAPY
Disclosed are methods of using planar or defocused acoustic waves for providing non-invasive sonodynamic therapy. The method includes acoustically coupling an array of piezoelectric transducers to a patient. A controller is configured to generate an electrical drive signal at a frequency selected from a range of frequencies, modulate the drive signal, and drive the transducer with the modulated drive signal at the frequency to produce modulated acoustic waves to produce an average acoustic intensity sufficient to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 26. Okt. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
AGARWAL VIJAY [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-10-26, Last update posted on www.tib.eu: 2023-11-09, Last updated: 2023-11-17 |
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| Patentnummer: |
US2023338751 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA018410472 |
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| 520 | |a Disclosed are methods of using planar or defocused acoustic waves for providing non-invasive sonodynamic therapy. The method includes acoustically coupling an array of piezoelectric transducers to a patient. A controller is configured to generate an electrical drive signal at a frequency selected from a range of frequencies, modulate the drive signal, and drive the transducer with the modulated drive signal at the frequency to produce modulated acoustic waves to produce an average acoustic intensity sufficient to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region. | ||
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a A61F: Filters implantable into blood vessels; prostheses; devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents; orthopaedic, nursing or contraceptive devices; fomentation; treatment or protection of eyes or ears; bandages, dressings or absorbent pads; first-aid kits (dental prosthetics a61c) | |
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
| 650 | 4 | |a B06B: Generating or transmitting mechanical vibrations in general (for particular physical or chemical processes, see the relevant subclasses, e.g. b07b0001400000, b22c0019060000, b23q0017120000, b24b0031060000, e01c0019220000;measurement of mechanical vibrations, including the combination of generation and measurement, g01h;systems using reflection or reradiation of acoustic waves g01s0015000000;generating seismic energy for prospecting g01v0001020000;control of mechanical vibrations g05d0019000000;methods or devices for transmitting, conducting or directing sound, in general g10k0011000000;synthesis of acoustic waves g10k0015020000;piezo-electric, electrostrictive or magnetostrictive elements h01l0041000000;motors with vibrating magnet, armature or coil h02k0033000000;motors using piezo-electric effect, electrostriction or magnetostriction h02n0002000000;generation of electrical oscillations h03b;electromechanical resonators as resonant circuit elements h03h;loudspeakers, microphones, gramophone pick-ups or like acoustic electromechanical transducers h04r) | |
| 650 | 4 | |a che | |
| 650 | 4 | |a med | |
| 650 | 4 | |a A61N: Electrotherapy; magnetotherapy; radiation therapy; ultrasound therapy (measurement of bioelectric currents a61b;surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body a61b0018000000;anaesthetic apparatus in general a61m;incandescent lamps h01k;infra-red radiators for heating h05b) | |
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