Colorectal cancer specific targeting exosome composition as a drug anticancer delivery and use thereof
The present invention relates to: a recombinant expression vector in which a gene expressing a ligand binding to a receptor of colorectal cancer cells is inserted into a gene expressed into extracellular vesicles of stem cells; a pharmaceutical composition comprising extracellular vesicles transformed by using the expression vector; and a method for preparing an expression vector for preventing or treating colorectal cancer. The present invention utilizes exosomes as extracellular vesicles as a drug delivery material and selectively binds to colorectal cancer cells, which are target cells, thereby providing an advantage of being able to have a specific action targeting colorectal cancer..
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Patent| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Europäisches Patentamt - (2022) vom: 07. Nov. Zur Gesamtaufnahme - year:2022 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
SAY JUNE KIM [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2022-11-07, Last update posted on www.tib.eu: 2023-11-08, Last updated: 2023-11-17 |
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| Patentnummer: |
KR20220148568 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA018400906 |
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| 520 | |a The present invention relates to: a recombinant expression vector in which a gene expressing a ligand binding to a receptor of colorectal cancer cells is inserted into a gene expressed into extracellular vesicles of stem cells; a pharmaceutical composition comprising extracellular vesicles transformed by using the expression vector; and a method for preparing an expression vector for preventing or treating colorectal cancer. The present invention utilizes exosomes as extracellular vesicles as a drug delivery material and selectively binds to colorectal cancer cells, which are target cells, thereby providing an advantage of being able to have a specific action targeting colorectal cancer. | ||
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| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
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