METHODS AND COMPOSITIONS FOR DISRUPTING TAU AGGREGATES USING POLYSERINE REPEAT SEQUENCES TARGETING EXOGENOUS PROTEINS
The present invention includes novel methods and compositions for targeting tau aggregates, or components thereof. In one specific embodiment, the invention include the novel use of polyserine repeat sequences, and/or serine-rich sequences, which may be coupled with a heterologous peptide, to target tau aggregates, or components thereof, and thereby localize the heterologous peptide to the tau aggregate..
| Medienart: |
|
|---|
Patent| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 07. Dez. Zur Gesamtaufnahme - year:2023 |
|---|
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
VAN ALSTYNE MEAGHAN [VerfasserIn] |
|---|
| Links: |
Volltext [kostenfrei] |
|---|
| Themen: |
Sonstige Themen: |
|---|
| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-12-07, Last update posted on www.tib.eu: 2024-01-31, Last updated: 2024-02-09 |
|---|
| Patentnummer: |
WO2023178241 |
|---|
| Förderinstitution / Projekttitel: |
|
|---|
| PPN (Katalog-ID): |
EPA018286992 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | EPA018286992 | ||
| 003 | DE-627 | ||
| 005 | 20240209083248.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231020s2023 xx |||||o 00| ||eng c | ||
| 035 | |a (DE-627)EPA018286992 | ||
| 035 | |a (EPA)WO2023178241 | ||
| 035 | |a (EPA)88024514 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 0 | |a VAN ALSTYNE MEAGHAN |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a METHODS AND COMPOSITIONS FOR DISRUPTING TAU AGGREGATES USING POLYSERINE REPEAT SEQUENCES TARGETING EXOGENOUS PROTEINS |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Source: www.epo.org (no modifications made), First posted: 2023-12-07, Last update posted on www.tib.eu: 2024-01-31, Last updated: 2024-02-09 | ||
| 520 | |a The present invention includes novel methods and compositions for targeting tau aggregates, or components thereof. In one specific embodiment, the invention include the novel use of polyserine repeat sequences, and/or serine-rich sequences, which may be coupled with a heterologous peptide, to target tau aggregates, or components thereof, and thereby localize the heterologous peptide to the tau aggregate. | ||
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a C07K: Peptides (peptides containing β-lactam rings c07d;cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, c07d;ergot alkaloids of the cyclic peptide type c07d0519020000; single cell proteins, enzymes c12n;genetic engineering processes for obtaining peptides c12n0015000000) | |
| 650 | 4 | |a che | |
| 650 | 4 | |a 615 | |
| 700 | 0 | |a PARKER ROY |4 aut | |
| 700 | 0 | |a LESTER EVAN |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Europäisches Patentamt |g (2023) vom: 07. Dez. |
| 773 | 1 | 8 | |g year:2023 |g day:07 |g month:12 |
| 856 | 4 | 0 | |u https://worldwide.espacenet.com/patent/search/family/88024514/publication/WO2023178241A1?q=WO2023178241 |z kostenfrei |3 Volltext |
| 912 | |a GBV_EPA | ||
| 936 | u | w | |j 2023 |b 07 |c 12 |
| 951 | |a AR | ||
| 952 | |j 2023 |b 07 |c 12 | ||