EXPRESSION CASSETTE OF INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN AND AAV-BASED GENE DELIVERY SYSTEM
The present invention relates to a nucleic acid molecule encoding an interleukin 1 receptor antagonist protein, a transgenic expression cassette comprising the nucleic acid molecule, a gene delivery system comprising the transgenic expression cassette and use thereof. The transgenic expression cassette and the gene delivery system of the present invention can be used to treat various diseases that can be improved by blocking the IL-1 signaling pathway, including malignant tumors and inflammatory diseases, such as arthritis, particularly osteoarthritis..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 07. Sept. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
XIAO XIAO [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-09-07, Last update posted on www.tib.eu: 2023-10-19, Last updated: 2023-10-27 |
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| Patentnummer: |
WO2023165477 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA018149650 |
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| 520 | |a The present invention relates to a nucleic acid molecule encoding an interleukin 1 receptor antagonist protein, a transgenic expression cassette comprising the nucleic acid molecule, a gene delivery system comprising the transgenic expression cassette and use thereof. The transgenic expression cassette and the gene delivery system of the present invention can be used to treat various diseases that can be improved by blocking the IL-1 signaling pathway, including malignant tumors and inflammatory diseases, such as arthritis, particularly osteoarthritis. | ||
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