Pharmaceutical composition of melatonin and vitamin E and application thereof
The invention relates to a melatonin and vitamin E pharmaceutical composition and application thereof. According to the invention, the novel application of combination of melatonin and vitamin E in preparation of ovarian anti-radiation drugs or drugs for treating ovarian ionizing radiation injury is confirmed for the first time; animal models prove that the pharmaceutical composition disclosed by the invention can be used for improving the estrus cycle disorder of irradiated mice, increasing the ovarian organ coefficient of the irradiated mice, improving the mouse ovarian hormone level disorder caused by irradiation and increasing the number of irradiated mouse follicles. The melatonin and the vitamin E can be used for treating the radiation-induced ovarian tissue injury, and a new hope is brought to the prevention of the radiation injury of the ovary..
| Medienart: |
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 23. Juni Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
CAI SHENGYUN [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Sonstige Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-06-23, Last update posted on www.tib.eu: 2024-03-04, Last updated: 2024-03-08 |
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| Patentnummer: |
CN116270618 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA018101402 |
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| 520 | |a The invention relates to a melatonin and vitamin E pharmaceutical composition and application thereof. According to the invention, the novel application of combination of melatonin and vitamin E in preparation of ovarian anti-radiation drugs or drugs for treating ovarian ionizing radiation injury is confirmed for the first time; animal models prove that the pharmaceutical composition disclosed by the invention can be used for improving the estrus cycle disorder of irradiated mice, increasing the ovarian organ coefficient of the irradiated mice, improving the mouse ovarian hormone level disorder caused by irradiation and increasing the number of irradiated mouse follicles. The melatonin and the vitamin E can be used for treating the radiation-induced ovarian tissue injury, and a new hope is brought to the prevention of the radiation injury of the ovary. | ||
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
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