Anti-renal fibrosis natural product Commiphorane C isomer as well as preparation method and application thereof
The invention discloses an anti-renal fibrosis natural product Commiphorane C isomer as well as a preparation method, a pharmaceutical composition and application thereof, and belongs to the technical field of medicines. The invention specifically relates to compounds represented by formulas Ia, Ib, Ic and Id or isomers and pharmaceutically acceptable salts thereof, and a preparation method thereof. A new pharmaceutical composition comprises effective doses of compounds of formulae Ia, Ib, Ic and Id and a pharmacodynamically acceptable carrier. The invention also discloses application of the compound in prevention and/or treatment of renal fibrosis and/or chronic renal failure caused by renal fibrosis..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 30. Juni Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
XIE PING [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-06-30, Last update posted on www.tib.eu: 2023-11-28, Last updated: 2023-12-01 |
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| Patentnummer: |
CN116354913 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA018100406 |
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| 520 | |a The invention discloses an anti-renal fibrosis natural product Commiphorane C isomer as well as a preparation method, a pharmaceutical composition and application thereof, and belongs to the technical field of medicines. The invention specifically relates to compounds represented by formulas Ia, Ib, Ic and Id or isomers and pharmaceutically acceptable salts thereof, and a preparation method thereof. A new pharmaceutical composition comprises effective doses of compounds of formulae Ia, Ib, Ic and Id and a pharmacodynamically acceptable carrier. The invention also discloses application of the compound in prevention and/or treatment of renal fibrosis and/or chronic renal failure caused by renal fibrosis. | ||
| 650 | 4 | |a C07D: Heterocyclic compounds (macromolecular compounds c08) | |
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
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