METHODS FOR PRODUCING OF LIPIDS
Methods for producing a compound of Formula I, Formula I, wherein R1 and R2 are independently a i) linear or branched or cyclic, ii) saturated or unsaturated, and iii) substituted or unsubstituted hydrocarbon group comprising 8 to 20 carbon atoms; R3 is a hydrocarbon group; n is an integer from 2 to 5, m is an integer from 30 to 70, and L is a linker. The method includes: a) contacting a fatty acid having a chemical formula of R1-COOH and a primary amine having a chemical formula of R2-NH2 to form an amide having a chemical formula of R1-C(O)-NH-R2; b) contacting the amide with a reducing agent to form a secondary amine having a chemical formula of R1-CH2-NH-R2; and c) contacting the secondary amine with a polyolefin-glycol compound to form the compound of Formula I. Intermediates produced in the method, salts of compound of Formula I and of intermediates..
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Patent| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Europäisches Patentamt - (2022) vom: 21. Juli Zur Gesamtaufnahme - year:2022 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
BROWN ADAM ROSS [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Sonstige Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2022-07-21, Last update posted on www.tib.eu: 2023-12-04, Last updated: 2023-12-08 |
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| Patentnummer: |
CA3208267 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA017940168 |
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| 245 | 1 | 0 | |a METHODS FOR PRODUCING OF LIPIDS |
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| 500 | |a Source: www.epo.org (no modifications made), First posted: 2022-07-21, Last update posted on www.tib.eu: 2023-12-04, Last updated: 2023-12-08 | ||
| 520 | |a Methods for producing a compound of Formula I, Formula I, wherein R1 and R2 are independently a i) linear or branched or cyclic, ii) saturated or unsaturated, and iii) substituted or unsubstituted hydrocarbon group comprising 8 to 20 carbon atoms; R3 is a hydrocarbon group; n is an integer from 2 to 5, m is an integer from 30 to 70, and L is a linker. The method includes: a) contacting a fatty acid having a chemical formula of R1-COOH and a primary amine having a chemical formula of R2-NH2 to form an amide having a chemical formula of R1-C(O)-NH-R2; b) contacting the amide with a reducing agent to form a secondary amine having a chemical formula of R1-CH2-NH-R2; and c) contacting the secondary amine with a polyolefin-glycol compound to form the compound of Formula I. Intermediates produced in the method, salts of compound of Formula I and of intermediates. | ||
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a che | |
| 650 | 4 | |a C07C: Acyclic or carbocyclic compounds (macromolecular compounds c08;production of organic compounds by electrolysis or electrophoresis c25b0003000000, c25b0007000000) | |
| 650 | 4 | |a 615 | |
| 700 | 0 | |a EISENBEIS SHANE ALLEN |4 aut | |
| 700 | 0 | |a HUBBELL ARAN KATHLEEN |4 aut | |
| 700 | 0 | |a LI RUIZHI |4 aut | |
| 700 | 0 | |a REYES GISELLE PADILLA |4 aut | |
| 700 | 0 | |a ROOSEN PHILIPP CHRISTOPHER |4 aut | |
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