CELL IMPERMEABLE KINASE INHIBITORS TO TREAT SARS-COV-2 AND/OR HSV VIRAL INFECTIONS
Methods of preventing or treating a coronavirus infection or a herpes simplex virus infection in a subject or preventing or treating a disease caused by a coronavirus infection or a herpes simplex virus infection in a subject are disclosed. The methods comprise administering to the subject an effective amount of a cell-impermeable inhibitor comprising a cell-impermeable kinase inhibitor, a cell-impermeable Akt inhibitor, an anti-Akt antibody, a cell-impermeable 3- phosphoinositide-dependent protein kinase- 1 (PDPK1) inhibitor, an anti-PDPKl antibody, or a combination thereof..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 19. Mai Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
HEROLD BETSY C [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-05-19, Last update posted on www.tib.eu: 2023-10-06, Last updated: 2023-10-13 |
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| Patentnummer: |
WO2023086547 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA017403308 |
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| 520 | |a Methods of preventing or treating a coronavirus infection or a herpes simplex virus infection in a subject or preventing or treating a disease caused by a coronavirus infection or a herpes simplex virus infection in a subject are disclosed. The methods comprise administering to the subject an effective amount of a cell-impermeable inhibitor comprising a cell-impermeable kinase inhibitor, a cell-impermeable Akt inhibitor, an anti-Akt antibody, a cell-impermeable 3- phosphoinositide-dependent protein kinase- 1 (PDPK1) inhibitor, an anti-PDPKl antibody, or a combination thereof. | ||
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| 650 | 4 | |a C07D: Heterocyclic compounds (macromolecular compounds c08) | |
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| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
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