SYSTEMS AND METHODS FOR PERSONALIZED TREATMENT OF TUMORS
Systems and methods for personalized treatment of tumors in accordance with embodiments of the invention are illustrated. One embodiment includes a method for determining prognosis for tumors, including obtaining a histological stain of a tumor, extracting a matrix ultrastructure of the tumor from the histological stain, obtaining an image of the tumor, where the image of the tumor is at sufficient resolution to demarcate individual cells, annotating each cell in the image with the respective cell type, determining cellular interactions between cells in the image based on the annotated cell types, providing the matrix ultrastructure and the cellular interactions to a prognosis model, obtaining an estimated survival time from the prognosis model..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 25. Mai Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
GUO JASON LIWEI [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-05-25, Last update posted on www.tib.eu: 2023-10-19, Last updated: 2023-10-27 |
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| Patentnummer: |
WO2023091967 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA017402662 |
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| 520 | |a Systems and methods for personalized treatment of tumors in accordance with embodiments of the invention are illustrated. One embodiment includes a method for determining prognosis for tumors, including obtaining a histological stain of a tumor, extracting a matrix ultrastructure of the tumor from the histological stain, obtaining an image of the tumor, where the image of the tumor is at sufficient resolution to demarcate individual cells, annotating each cell in the image with the respective cell type, determining cellular interactions between cells in the image based on the annotated cell types, providing the matrix ultrastructure and the cellular interactions to a prognosis model, obtaining an estimated survival time from the prognosis model. | ||
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| 650 | 4 | |a G06T: Image data processing or generation, in general | |
| 650 | 4 | |a A61B: Diagnosis; surgery; identification (analysing biological material g01n, e.g. g01n0033480000) | |
| 650 | 4 | |a G01N: Investigating or analysing materials by determining their chemical or physical properties (measuring or testing processes other than immunoassay, involving enzymes or microorganisms c12m, c12q) | |
| 650 | 4 | |a G16H: Healthcare informatics, i.e. information and communication technology [ict] specially adapted for the handling or processing of medical or healthcare data | |
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