Mitochondrial targeting fluorescent probe as well as preparation method and application thereof
The invention relates to a mitochondrial targeting fluorescent probe as well as a preparation method and application thereof. The compound comprises at least one of a compound shown in a formula (I), a compound shown in a formula (II) and a compound shown in a formula (III). The water-soluble red-to-near-infrared mitochondrial targeting fluorescent probe provided by the invention has the advantages of high quantum yield, good water solubility, good biocompatibility, strong light stability and the like, can accurately target mitochondria for imaging and tracking, has relatively low phototoxicity, and can be used for long-time mitochondrial imaging..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 28. März Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
JIANG FENGLEI [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-03-28, Last update posted on www.tib.eu: 2023-06-27, Last updated: 2023-06-30 |
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| Patentnummer: |
CN115850311 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA017246237 |
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| 520 | |a The invention relates to a mitochondrial targeting fluorescent probe as well as a preparation method and application thereof. The compound comprises at least one of a compound shown in a formula (I), a compound shown in a formula (II) and a compound shown in a formula (III). The water-soluble red-to-near-infrared mitochondrial targeting fluorescent probe provided by the invention has the advantages of high quantum yield, good water solubility, good biocompatibility, strong light stability and the like, can accurately target mitochondria for imaging and tracking, has relatively low phototoxicity, and can be used for long-time mitochondrial imaging. | ||
| 650 | 4 | |a cet | |
| 650 | 4 | |a che | |
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a C07F: Acyclic, carbocyclic, or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium (metal-containing porphyrins c07d0487220000;macromolecular compounds c08) | |
| 650 | 4 | |a C09K: Materials for applications not otherwise provided for; applications of materials not otherwise provided for | |
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