Alpha-carboline compound or pharmaceutical composition thereof as well as preparation method and application of alpha-carboline compound
The invention discloses an alpha-carboline compound or a pharmaceutical composition thereof as well as a preparation method and application of the alpha-carboline compound, and the alpha-carboline compound is N1-substituted quaternary ammonium salt, can effectively inhibit the activity of cholinesterase AChE and BuChE, has anti-neuritis activity, and can be used for preparing anti-neuritis drugs. The compound can be developed into drugs for preventing and/or treating neurodegenerative diseases (such as Alzheimer's disease), neuritis diseases and other related diseases..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 28. März Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
DAI JIANGKUN [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-03-28, Last update posted on www.tib.eu: 2023-06-27, Last updated: 2023-06-30 |
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| Patentnummer: |
CN115850270 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA017246113 |
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| 520 | |a The invention discloses an alpha-carboline compound or a pharmaceutical composition thereof as well as a preparation method and application of the alpha-carboline compound, and the alpha-carboline compound is N1-substituted quaternary ammonium salt, can effectively inhibit the activity of cholinesterase AChE and BuChE, has anti-neuritis activity, and can be used for preparing anti-neuritis drugs. The compound can be developed into drugs for preventing and/or treating neurodegenerative diseases (such as Alzheimer's disease), neuritis diseases and other related diseases. | ||
| 650 | 4 | |a C07D: Heterocyclic compounds (macromolecular compounds c08) | |
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
| 650 | 4 | |a che | |
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
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