Application of cucurbitacine E in preparation of medicine for preventing or treating adrenal cortex cancer
The invention relates to application of cucurbitacine E in preparation of a medicine for preventing or treating adrenal cortex cancer, and belongs to the technical field of medicines. The cucurbitacine E provided by the invention can inhibit proliferation of adrenal cortex cancer cells. The anti-tumor effect is achieved by inhibiting DNA replication of adrenal cortex cancer cells and retarding the cell cycle, so that cell apoptosis is induced. In addition, the cucurbitacin E can inhibit tumors by inhibiting migration and invasion of adrenal cortex cancer cells..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 03. Feb. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
WANG JINHUA [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Sonstige Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-02-03, Last update posted on www.tib.eu: 2023-06-07, Last updated: 2023-06-16 |
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| Patentnummer: |
CN115671115 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA017155762 |
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| 520 | |a The invention relates to application of cucurbitacine E in preparation of a medicine for preventing or treating adrenal cortex cancer, and belongs to the technical field of medicines. The cucurbitacine E provided by the invention can inhibit proliferation of adrenal cortex cancer cells. The anti-tumor effect is achieved by inhibiting DNA replication of adrenal cortex cancer cells and retarding the cell cycle, so that cell apoptosis is induced. In addition, the cucurbitacin E can inhibit tumors by inhibiting migration and invasion of adrenal cortex cancer cells. | ||
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
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| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
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