Novel coronavirus vaccine polypeptide and application of nanoemulsion preparation of novel coronavirus vaccine polypeptide in prevention of infection of novel coronavirus strain and mutant strain
The invention discloses a coronavirus SARS-CoV-2 vaccine polypeptide, a polypeptide composition and application of a nanoemulsion preparation of the polypeptide composition in prevention of infection of a coronavirus SARS-CoV-2 wild strain and a mutant strain. Specifically, the invention provides a coronavirus SARS-CoV-2 vaccine polypeptide with an amino acid sequence derived from S protein of an SARS-CoV-2 wild strain and a mutant strain, and the vaccine polypeptide provided by the invention can enable an organism to generate a high-level and lasting humoral immune response aiming at the SARS-CoV-2, generate a high-titer RBD binding antibody and a neutralizing antibody for blocking the binding of RBD and ACE2. The vaccine polypeptide disclosed by the invention can be used for preventing infection of a variety of mutant strains such as SARS-CoV-2 wild strains, B.1. 1.7, B.1.351, B.1.617 and the like..
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Patent| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Europäisches Patentamt - (2022) vom: 02. Dez. Zur Gesamtaufnahme - year:2022 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
GONG LIKUN [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2022-12-02, Last update posted on www.tib.eu: 2023-06-27, Last updated: 2023-06-30 |
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| Patentnummer: |
CN115417917 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA016775260 |
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| 245 | 1 | 0 | |a Novel coronavirus vaccine polypeptide and application of nanoemulsion preparation of novel coronavirus vaccine polypeptide in prevention of infection of novel coronavirus strain and mutant strain |
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| 520 | |a The invention discloses a coronavirus SARS-CoV-2 vaccine polypeptide, a polypeptide composition and application of a nanoemulsion preparation of the polypeptide composition in prevention of infection of a coronavirus SARS-CoV-2 wild strain and a mutant strain. Specifically, the invention provides a coronavirus SARS-CoV-2 vaccine polypeptide with an amino acid sequence derived from S protein of an SARS-CoV-2 wild strain and a mutant strain, and the vaccine polypeptide provided by the invention can enable an organism to generate a high-level and lasting humoral immune response aiming at the SARS-CoV-2, generate a high-titer RBD binding antibody and a neutralizing antibody for blocking the binding of RBD and ACE2. The vaccine polypeptide disclosed by the invention can be used for preventing infection of a variety of mutant strains such as SARS-CoV-2 wild strains, B.1. 1.7, B.1.351, B.1.617 and the like. | ||
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| 650 | 4 | |a C07K: Peptides (peptides containing β-lactam rings c07d;cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, c07d;ergot alkaloids of the cyclic peptide type c07d0519020000; single cell proteins, enzymes c12n;genetic engineering processes for obtaining peptides c12n0015000000) | |
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