Application of VER50589 in preparation of medicine for resisting enterovirus 71
The invention provides an application of VER50589 in preparation of an anti-EV71 (enterovirus 71) drug, an HSP90 beta inhibitor (VER-50589) has certain EV71 inhibition activity, can strongly inhibit RD cell lesion effect caused by EV71 virus, enhance cell survival rate, inhibit virus RNA (ribonucleic acid) level replication and significantly reduce death rate of infected mice, and can be applied in preparation of the anti-EV71 virus drug..
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Patent| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Europäisches Patentamt - (2022) vom: 25. Nov. Zur Gesamtaufnahme - year:2022 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
ZHANG DINGYU [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Sonstige Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2022-11-25, Last update posted on www.tib.eu: 2023-06-27, Last updated: 2023-06-30 |
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| Patentnummer: |
CN115381816 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA016514475 |
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| 520 | |a The invention provides an application of VER50589 in preparation of an anti-EV71 (enterovirus 71) drug, an HSP90 beta inhibitor (VER-50589) has certain EV71 inhibition activity, can strongly inhibit RD cell lesion effect caused by EV71 virus, enhance cell survival rate, inhibit virus RNA (ribonucleic acid) level replication and significantly reduce death rate of infected mice, and can be applied in preparation of the anti-EV71 virus drug. | ||
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
| 650 | 4 | |a che | |
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
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