CRHR1 Dimethylpyrazolotriazin derivatives preparation method thereof and pharmaceutical composition for use in preventing or treating CRHR1 related diseases containing the same as an active ingredient
The present invention relates to a dimethylpyrazolotriazine derivative, a method for manufacturing the same, and a pharmaceutical composition for preventing or treating CRHR1-related diseases comprising the same as an active ingredient. The compound represented by chemical formula 1 described herein has remarkably excellent metabolic stability. In addition, while exhibiting an excellent antagonistic effect on CRHR1, the present invention exhibits excellent effects in animal behavior experiments to confirm an antidepressant effect, thereby being expected to be useful for CRHR1-related diseases..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 27. Jan. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
KIM BYEONG MOON [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-01-27, Last update posted on www.tib.eu: 2024-02-27, Last updated: 2024-03-01 |
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| Patentnummer: |
KR20230013707 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA016408594 |
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| 520 | |a The present invention relates to a dimethylpyrazolotriazine derivative, a method for manufacturing the same, and a pharmaceutical composition for preventing or treating CRHR1-related diseases comprising the same as an active ingredient. The compound represented by chemical formula 1 described herein has remarkably excellent metabolic stability. In addition, while exhibiting an excellent antagonistic effect on CRHR1, the present invention exhibits excellent effects in animal behavior experiments to confirm an antidepressant effect, thereby being expected to be useful for CRHR1-related diseases. | ||
| 650 | 4 | |a C07D: Heterocyclic compounds (macromolecular compounds c08) | |
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