Application of ITGA6 positive iPSC source trabecular meshwork cells in preparation of drugs for treating intraocular hypertension diseases and screening method of ITGA6 positive iPSC source trabecular meshwork cells
The invention provides application of ITGA6 positive iPSC source trabecular meshwork cells in preparation of drugs for treating intraocular hypertension diseases and a screening method, belongs to the technical field of cell therapy, and particularly relates to application of ITGA6 positive iPSC-TM cell samples in preparation of drugs for treating intraocular hypertension diseases. The invention also provides a method for screening an ITGA6 positive iPSC-TM cell sample, and the method mainly comprises the following steps: mixing human-derived iPSC-TM cells with an FITC-ITGA6 antibody, and adding magnetic beads with Anti-FITC to prepare a magnetic bead cell mixture; and purifying the LS sorting strain in a magnetic field, and screening a cell sample with the ITGA6 positive iPSC-TM cell ratio of 5.8% or above..
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Patent| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Europäisches Patentamt - (2022) vom: 30. Dez. Zur Gesamtaufnahme - year:2022 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
ZHU WEI [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2022-12-30, Last update posted on www.tib.eu: 2023-06-29, Last updated: 2023-07-08 |
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| Patentnummer: |
CN115531417 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA016354354 |
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| 245 | 1 | 0 | |a Application of ITGA6 positive iPSC source trabecular meshwork cells in preparation of drugs for treating intraocular hypertension diseases and screening method of ITGA6 positive iPSC source trabecular meshwork cells |
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| 520 | |a The invention provides application of ITGA6 positive iPSC source trabecular meshwork cells in preparation of drugs for treating intraocular hypertension diseases and a screening method, belongs to the technical field of cell therapy, and particularly relates to application of ITGA6 positive iPSC-TM cell samples in preparation of drugs for treating intraocular hypertension diseases. The invention also provides a method for screening an ITGA6 positive iPSC-TM cell sample, and the method mainly comprises the following steps: mixing human-derived iPSC-TM cells with an FITC-ITGA6 antibody, and adding magnetic beads with Anti-FITC to prepare a magnetic bead cell mixture; and purifying the LS sorting strain in a magnetic field, and screening a cell sample with the ITGA6 positive iPSC-TM cell ratio of 5.8% or above. | ||
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| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
| 650 | 4 | |a che | |
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