Compositions and methods for modulating follicular formation to treat ovarian aging
Provided herein are methods and compositions related to modified proteins of anti-mullerian hormone (AMH) for modulating follicular production in women, in particular for modulating activation and maturation of follicles as well as depletion of immature (original) follicles. In certain embodiments, a method is disclosed. Modulation or inhibition of follicular production in a female can treat ovarian aging, suspend or slow ovarian aging, and/or delay the onset of menopause and/or symptoms associated with menopause, premature ovarian failure caused by gonad toxicity therapy, or diseases or conditions caused by genetic mutations in genes that modulate follicular production and ovarian biology..
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Patent| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Europäisches Patentamt - (2022) vom: 04. Nov. Zur Gesamtaufnahme - year:2022 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
BEHM PIRAJ JURTAS [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2022-11-04, Last update posted on www.tib.eu: 2023-11-21, Last updated: 2023-11-24 |
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| Patentnummer: |
CN115297929 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA016232755 |
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| 520 | |a Provided herein are methods and compositions related to modified proteins of anti-mullerian hormone (AMH) for modulating follicular production in women, in particular for modulating activation and maturation of follicles as well as depletion of immature (original) follicles. In certain embodiments, a method is disclosed. Modulation or inhibition of follicular production in a female can treat ovarian aging, suspend or slow ovarian aging, and/or delay the onset of menopause and/or symptoms associated with menopause, premature ovarian failure caused by gonad toxicity therapy, or diseases or conditions caused by genetic mutations in genes that modulate follicular production and ovarian biology. | ||
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| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
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