Application of gallocatechin gallate in preparation of medicine for treating new coronavirus or sepsis
The invention provides application of gallocatechin gallate, and pharmaceutically acceptable salt, prodrug or hydrate of the gallocatechin gallate in preparation of medicines for preventing and/or treating diseases caused by coronavirus or sepsis. The inventor found, and confirmed through experiments, that the epigallocatechin gallate can significantly inhibit the coronavirus, and the epigallocatechin gallate has a synergistic effect when used in combination with another Mpro inhibitor-ebselin (Ebselin); in addition, the epigallocatechin gallate can effectively inhibit sepsis, so that the epigallocatechin gallate is a promising candidate drug for treating diseases (especially COVID-19 caused by SARS-CoV-2) caused by coronavirus and sepsis..
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Patent| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Europäisches Patentamt - (2021) vom: 31. Dez. Zur Gesamtaufnahme - year:2021 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
ZHOU HONGGANG [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2021-12-31, Last update posted on www.tib.eu: 2022-11-24, Last updated: 2023-02-09 |
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| Patentnummer: |
CN113855667 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA016071999 |
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| 520 | |a The invention provides application of gallocatechin gallate, and pharmaceutically acceptable salt, prodrug or hydrate of the gallocatechin gallate in preparation of medicines for preventing and/or treating diseases caused by coronavirus or sepsis. The inventor found, and confirmed through experiments, that the epigallocatechin gallate can significantly inhibit the coronavirus, and the epigallocatechin gallate has a synergistic effect when used in combination with another Mpro inhibitor-ebselin (Ebselin); in addition, the epigallocatechin gallate can effectively inhibit sepsis, so that the epigallocatechin gallate is a promising candidate drug for treating diseases (especially COVID-19 caused by SARS-CoV-2) caused by coronavirus and sepsis. | ||
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| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
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