Formulations of PTHrP analogs, transdermal patches thereof, and uses thereof
The invention relates to the field of osteoporosis treatment, in particular to a preparation of a PTHrP analogue, a transdermal patch of the PTHrP analogue and application of the PTHrP analogue, and the prepared preparation comprises a therapeutic active substance, water and one or more excipients selected from Zn < 2 + > salt, Mg < 2 + > salt, Ca < 2 + > salt, polyethylene glycol and hydroxypropyl beta-cyclodextrin. The present invention relates to a PTHrP analogue formulation for transdermal delivery of a therapeutically effective amount of a PTHrP analogue, and methods of treating osteoporosis, osteopenia, osteoarthritis and/or fractures, improving bone mineral density (BMD), improving trabecular bone score (TBS), and treating, preventing and/or reducing fractures using these formulations and patches..
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Patent| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Europäisches Patentamt - (2022) vom: 09. Sept. Zur Gesamtaufnahme - year:2022 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
HATTERSLEY GARY [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Sonstige Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2022-09-09, Last update posted on www.tib.eu: 2024-02-26, Last updated: 2024-03-01 |
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| Patentnummer: |
CN115025068 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA015487814 |
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| 520 | |a The invention relates to the field of osteoporosis treatment, in particular to a preparation of a PTHrP analogue, a transdermal patch of the PTHrP analogue and application of the PTHrP analogue, and the prepared preparation comprises a therapeutic active substance, water and one or more excipients selected from Zn < 2 + > salt, Mg < 2 + > salt, Ca < 2 + > salt, polyethylene glycol and hydroxypropyl beta-cyclodextrin. The present invention relates to a PTHrP analogue formulation for transdermal delivery of a therapeutically effective amount of a PTHrP analogue, and methods of treating osteoporosis, osteopenia, osteoarthritis and/or fractures, improving bone mineral density (BMD), improving trabecular bone score (TBS), and treating, preventing and/or reducing fractures using these formulations and patches. | ||
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