Dosage form with sustained release melatonin pellets

A composition comprises a therapeutically effective oral pharmaceutical dosage form. The dosage form includes an aqueous carrier material having an acidic pH and a plurality of individual pellets having a first dose of melatonin therein. The individual pellets comprises (i) a solid core; (ii) an active coating over the solid core, the active coating including melatonin and a hydrophilic binder; and (iii) an enteric coating over the active coating. A dissolution pH of the enteric coating is higher than the acidic pH of the aqueous carrier material..

Medienart:

Patent

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Europäisches Patentamt - (2022) vom: 09. Juni Zur Gesamtaufnahme - year:2022

Sprache:

Englisch

Beteiligte Personen:

SHAH SYED M [VerfasserIn]
HASSAN DANIEL [VerfasserIn]

Links:

Volltext [kostenfrei]

Themen:

Sonstige Themen:
615
A61K: Preparations for medical, dental, or toilet purpose (...)
che

Anmerkungen:

Source: www.epo.org (no modifications made), First posted: 2022-06-09, Last update posted on www.tib.eu: 2023-06-03, Last updated: 2023-06-06

Patentnummer:

AU2021207284

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

EPA015312461