ANTIBODIES

The invention relates to antibodies and antigen-binding fragments thereof that recognize coronavirus spike proteins(CoV-S), such asthe spike protein of Middle East respiratory syndrome coronavirusspike protein(MERS-S). In some embodiments, the antibodiesbind to CoV-Swith high affinity, inhibit CoV infection of human cells, inhibit CoV sialic acid-binding activity and/or bind to multiple types of CoV-S. In some embodiments, the antibodies provide a means of preventing, treating or ameliorating CoV infection..

Medienart:

Patent

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Europäisches Patentamt - (2022) vom: 01. Sept. Zur Gesamtaufnahme - year:2022

Sprache:

Englisch

Beteiligte Personen:

GROSVELD FRANKLIN GERARDUS [VerfasserIn]
VAN HAPEREN MARINUS JOHANNES [VerfasserIn]
DRABEK DUBRAVKA [VerfasserIn]
BOSCH BEREND JAN [VerfasserIn]
WIDJAJA IVY [VerfasserIn]
WANG CHUNYAN [VerfasserIn]
VAN DIEREN BRENDA [VerfasserIn]
LI WENTAO [VerfasserIn]
VAN KUPPEVELD FRANK J M [VerfasserIn]
HAAGMANS BART L [VerfasserIn]
OKBA NISREEN M A [VerfasserIn]

Links:

Volltext [kostenfrei]

Themen:

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Anmerkungen:

Source: www.epo.org (no modifications made), First posted: 2022-09-01, Last update posted on www.tib.eu: 2024-02-27, Last updated: 2024-03-01

Patentnummer:

US2022275059

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

EPA014796791