Hydrazone derivatives for preventing or treating EBV-related cancers
The present invention relates to novel bis-hydrazone derivatives of formula (I):wherein Ar1 and Ar2 may be identical or different and are each independently selected from the group consisting of groups of formula (II) and (III):Y1 and Z1 are independently CH or NRc+, provided that al least one of Y1 and Z1 is NRc+ and at least one of Y1 and Z1 is CH,and Ra, Rb, Rc, X2− and L as defined in the claims, or a hydrate or a solvate thereof.Compositions and kits comprising same are also described. Said bis-hydrazone derivatives of formula (I), compositions and kits are useful as drugs, in particular for treating or preventing cancers associated with the Epstein-Barr Virus..
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Patent| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Europäisches Patentamt - (2022) vom: 09. Aug. Zur Gesamtaufnahme - year:2022 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
BLONDEL MARC [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2022-08-09, Last update posted on www.tib.eu: 2023-09-21, Last updated: 2023-09-22 |
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| Patentnummer: |
US11406631 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA014516012 |
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| 520 | |a The present invention relates to novel bis-hydrazone derivatives of formula (I):wherein Ar1 and Ar2 may be identical or different and are each independently selected from the group consisting of groups of formula (II) and (III):Y1 and Z1 are independently CH or NRc+, provided that al least one of Y1 and Z1 is NRc+ and at least one of Y1 and Z1 is CH,and Ra, Rb, Rc, X2− and L as defined in the claims, or a hydrate or a solvate thereof.Compositions and kits comprising same are also described. Said bis-hydrazone derivatives of formula (I), compositions and kits are useful as drugs, in particular for treating or preventing cancers associated with the Epstein-Barr Virus. | ||
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