Application of oridonin and/or prodrug thereof in preparation of medicine for inhibiting SARS-CoV-2
The invention provides application of oridonin and/or a prodrug thereof in preparation of a medicine for inhibiting SARS-CoV-2. The oridonin can target Mpro protease in the SARS-CoV-2 and significantly inhibit the enzyme activity, effectively inhibits the RNA replication of the SARS-CoV-2 and reduces the activity of the SARS-CoV-2, it is indicated that the small molecule oridonin can be used for treating or preventing the novel coronavirus pneumonia infected by the SARS-CoV-2 and an efficient, safe and novel natural medicine source without toxic and side effects is provided for treatment of novel coronavirus pneumonia..
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Patent| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Europäisches Patentamt - (2021) vom: 31. Dez. Zur Gesamtaufnahme - year:2021 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
SUN LITAO [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2021-12-31, Last update posted on www.tib.eu: 2022-10-03, Last updated: 2023-02-09 |
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| Patentnummer: |
CN113855665 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA013851810 |
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| 520 | |a The invention provides application of oridonin and/or a prodrug thereof in preparation of a medicine for inhibiting SARS-CoV-2. The oridonin can target Mpro protease in the SARS-CoV-2 and significantly inhibit the enzyme activity, effectively inhibits the RNA replication of the SARS-CoV-2 and reduces the activity of the SARS-CoV-2, it is indicated that the small molecule oridonin can be used for treating or preventing the novel coronavirus pneumonia infected by the SARS-CoV-2 and an efficient, safe and novel natural medicine source without toxic and side effects is provided for treatment of novel coronavirus pneumonia. | ||
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
| 650 | 4 | |a che | |
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
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