USE OF SOLUBLE NRP1 POLYPEPTIDES FOR THE TREATMENT OF CORONAVIRUS INFECTIONS

The present application relates to the treatment of coronavirus infection such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related diseases. The treatment is achieved by the administration of soluble neuropilin-1 (NRP1) polypeptides that compete with endogenous NRP1 and ACE2 for binding to the spike (S) glycoprotein from the coronavirus envelope..

Medienart:

Patent

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Europäisches Patentamt - (2021) vom: 30. Dez. Zur Gesamtaufnahme - year:2021

Sprache:

Englisch

Beteiligte Personen:

SAPIEHA PRZEMYSLAW [VerfasserIn]
BEAULIEU NORMAND [VerfasserIn]

Links:

Volltext [kostenfrei]

Themen:

615
A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d)
A61P: Specific therapeutic activity of chemical compounds or medicinal preparations
C07K: Peptides (peptides containing β-lactam rings c07d;cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, c07d;ergot alkaloids of the cyclic peptide type c07d0519020000; single cell proteins, enzymes c12n;genetic engineering processes for obtaining peptides c12n0015000000)
Che

Anmerkungen:

Source: www.epo.org (no modifications made), First posted: 2021-12-30, Last update posted on www.tib.eu: 2022-09-12, Last updated: 2023-02-09

Patentnummer:

WO2021258218

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

EPA013574736