METHODS AND COMPOSITIONS FOR TREATING CANCER BY TARGETING FATP2 AND MYELOID DERIVED SUPPRESSOR CELLS
A method of treating cancer in a subject in need thereof is provided. The method includes administering an agent that inhibits, decreases, deletes or downregulates FATP2. In one embodiment, the method includes administering a checkpoint inhibitor. Also provided are methods of decreasing MDSCs and MDSC immune-suppressive activity in a subject in need thereof..
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Patent| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Europäisches Patentamt - (2022) vom: 31. März Zur Gesamtaufnahme - year:2022 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
GABRILOVICH DMITRY I [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2022-03-31, Last update posted on www.tib.eu: 2022-08-14, Last updated: 2023-02-09 |
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| Patentnummer: |
US2022096484 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA013042319 |
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| 520 | |a A method of treating cancer in a subject in need thereof is provided. The method includes administering an agent that inhibits, decreases, deletes or downregulates FATP2. In one embodiment, the method includes administering a checkpoint inhibitor. Also provided are methods of decreasing MDSCs and MDSC immune-suppressive activity in a subject in need thereof. | ||
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