METHODS FOR CELL LABELING AND MEDICAL IMAGING
The present disclosure relates to a method of ex vivo labeling of a biological material for in vivo imaging. The method comprises contacting a biological material ex vivo with a labeling agent such that the biological material becomes labeled for in vivo imaging. The labeling agent comprises a chelating moiety, a conjugation moiety, and at least one of (i) a radionuclide and (ii) a paramagnetic metal ion or compound. The biological material is selected from viruses. The disclosure also relates to an imaging method comprising acquiring an image of a subject to whom a detectable amount of biological material labeled according to the disclosure has been administered..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 26. Juli Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
BANSAL ADITYA [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Sonstige Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-07-26, Last update posted on www.tib.eu: 2024-01-23, Last updated: 2024-01-26 |
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| Patentnummer: |
EP3973998 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA012989118 |
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| 520 | |a The present disclosure relates to a method of ex vivo labeling of a biological material for in vivo imaging. The method comprises contacting a biological material ex vivo with a labeling agent such that the biological material becomes labeled for in vivo imaging. The labeling agent comprises a chelating moiety, a conjugation moiety, and at least one of (i) a radionuclide and (ii) a paramagnetic metal ion or compound. The biological material is selected from viruses. The disclosure also relates to an imaging method comprising acquiring an image of a subject to whom a detectable amount of biological material labeled according to the disclosure has been administered. | ||
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