ANTIBODY PRODUCED BY USING AFUCOSYLATED N.BENTHAMIANA AND USES THEREOF
The present invention relates to an antibody produced using afucosylated N.benthamiana and uses thereof. It was confirmed that the antibody produced using afucosylated N.benthamiana according to the present invention has a sugar chain in a different form from that of an antibody produced using existing animal cells, and that fucose is not present in the sugar chain of the antibody. In addition, it was confirmed that the antibody having the modified sugar chain according to the present invention exhibits superior anticancer effects than the antibody produced using existing animal cells. Therefore, the antibody having the modified sugar chain according to the present invention can be usefully used for the prevention or treatment of cancer..
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Patent| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Europäisches Patentamt - (2021) vom: 31. Mai Zur Gesamtaufnahme - year:2021 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
CHOE SUNG HWA [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2021-05-31, Last update posted on www.tib.eu: 2022-08-21, Last updated: 2023-02-09 |
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| Patentnummer: |
KR20210062588 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA01191842X |
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| 520 | |a The present invention relates to an antibody produced using afucosylated N.benthamiana and uses thereof. It was confirmed that the antibody produced using afucosylated N.benthamiana according to the present invention has a sugar chain in a different form from that of an antibody produced using existing animal cells, and that fucose is not present in the sugar chain of the antibody. In addition, it was confirmed that the antibody having the modified sugar chain according to the present invention exhibits superior anticancer effects than the antibody produced using existing animal cells. Therefore, the antibody having the modified sugar chain according to the present invention can be usefully used for the prevention or treatment of cancer. | ||
| 650 | 4 | |a C12N: Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media (microbiological testing media c12q0001000000) | |
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
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| 650 | 4 | |a C07K: Peptides (peptides containing β-lactam rings c07d;cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, c07d;ergot alkaloids of the cyclic peptide type c07d0519020000; single cell proteins, enzymes c12n;genetic engineering processes for obtaining peptides c12n0015000000) | |
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