PARATHYROID HORMONE 1-34 NASAL SPRAY, PREPARATION METHOD AND APPLICATION THEREOF
A parathyroid hormone 1-34 pharmaceutical composition and a preparation method thereof, specifically relating to a parathyroid hormone 1-34 pharmaceutical composition including parathyroid hormone 1-34 as an active ingredient and a pharmaceutically acceptable vector, the vector at least comprising a buffer liquid, a penetration enhancer, a stabilizer and a preservative. The parathyroid hormone 1-34 pharmaceutical composition is a parathyroid hormone 1-34 nasal spray or nasal spray composition. A parathyroid hormone 1-34 nasal spray or nasal spray composition prepared by means of the present method has the advantages of preventing the first pass effect, leading to high bioavailability; rapid onset of action; and convenient administration, strengthening patient compliance and being absorbed into the nasal mucosa when used, which may effectively reduce the pain of polypeptide drug injection..
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Patent| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Europäisches Patentamt - (2021) vom: 14. Mai Zur Gesamtaufnahme - year:2021 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
ZHENG AIPING [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2021-05-14, Last update posted on www.tib.eu: 2022-07-02, Last updated: 2023-02-09 |
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| Patentnummer: |
WO2021088585 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA011677317 |
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| 520 | |a A parathyroid hormone 1-34 pharmaceutical composition and a preparation method thereof, specifically relating to a parathyroid hormone 1-34 pharmaceutical composition including parathyroid hormone 1-34 as an active ingredient and a pharmaceutically acceptable vector, the vector at least comprising a buffer liquid, a penetration enhancer, a stabilizer and a preservative. The parathyroid hormone 1-34 pharmaceutical composition is a parathyroid hormone 1-34 nasal spray or nasal spray composition. A parathyroid hormone 1-34 nasal spray or nasal spray composition prepared by means of the present method has the advantages of preventing the first pass effect, leading to high bioavailability; rapid onset of action; and convenient administration, strengthening patient compliance and being absorbed into the nasal mucosa when used, which may effectively reduce the pain of polypeptide drug injection. | ||
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
| 650 | 4 | |a che | |
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
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