COMPOSITIONS AND METHODS FOR PROTEIN EXPRESSION AND DELIVERY
Methods and compositions that provide an environment that promotes enhanced protein expression and/or folding are provided. More particularly, engineered thermostable ferritin assemblies capable of encapsulating polypeptides, nucleic acids or small molecules, which includes a modified ferritin subunit which lacks an unstructured carboxy-terminal sequence are provided. Methods and compositions for delivery of protein therapeutics are also provided..
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Patent| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Europäisches Patentamt - (2021) vom: 22. Apr. Zur Gesamtaufnahme - year:2021 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
DRUM CHESTER LEE [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Sonstige Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2021-04-22, Last update posted on www.tib.eu: 2023-10-06, Last updated: 2023-10-13 |
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| Patentnummer: |
US2021113484 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA011594640 |
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| 520 | |a Methods and compositions that provide an environment that promotes enhanced protein expression and/or folding are provided. More particularly, engineered thermostable ferritin assemblies capable of encapsulating polypeptides, nucleic acids or small molecules, which includes a modified ferritin subunit which lacks an unstructured carboxy-terminal sequence are provided. Methods and compositions for delivery of protein therapeutics are also provided. | ||
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| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a C07K: Peptides (peptides containing β-lactam rings c07d;cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, c07d;ergot alkaloids of the cyclic peptide type c07d0519020000; single cell proteins, enzymes c12n;genetic engineering processes for obtaining peptides c12n0015000000) | |
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