Application of diselenide compound as coronavirus 3C-like protease inhibitor, inhibitor and drug
The invention belongs to the technical field of medicinal chemistry, and particularly relates to a new application of a diselenide compound to preparation of an anti-coronavirus infection drug and thedrug. The invention discloses an application of a diselenide compound as a coronavirus 3C-like protease inhibitor. The invention also provides a coronavirus 3C-like protease inhibitor, and the activecomponent of the inhibitor is a diselenide compound. The coronavirus 3C-like protease inhibitor can be used for preparing drugs for resisting coronavirus infection. Experiments prove that the diselenide compound provided by the invention has a remarkable inhibition effect on the novel coronavirus 3C-like protease, and prompts that the diselenide compound can be used as the coronavirus 3C-like protease inhibitor and used for preparing anti-coronavirus inflammation drugs, thereby providing a new thought for treating novel coronavirus pneumonia..
Medienart: |
Patent |
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Erscheinungsjahr: |
2020 |
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Erschienen: |
2020 |
Enthalten in: |
Europäisches Patentamt - (2020) vom: 29. Dez. Zur Gesamtaufnahme - year:2020 |
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Sprache: |
Englisch |
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Beteiligte Personen: |
HAN KELI [VerfasserIn] |
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Links: |
Volltext [kostenfrei] |
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Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2020-12-29, Last update posted on www.tib.eu: 2022-04-10, Last updated: 2023-02-09 |
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Patentnummer: |
CN112137991 |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
EPA011480459 |
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520 | |a The invention belongs to the technical field of medicinal chemistry, and particularly relates to a new application of a diselenide compound to preparation of an anti-coronavirus infection drug and thedrug. The invention discloses an application of a diselenide compound as a coronavirus 3C-like protease inhibitor. The invention also provides a coronavirus 3C-like protease inhibitor, and the activecomponent of the inhibitor is a diselenide compound. The coronavirus 3C-like protease inhibitor can be used for preparing drugs for resisting coronavirus infection. Experiments prove that the diselenide compound provided by the invention has a remarkable inhibition effect on the novel coronavirus 3C-like protease, and prompts that the diselenide compound can be used as the coronavirus 3C-like protease inhibitor and used for preparing anti-coronavirus inflammation drugs, thereby providing a new thought for treating novel coronavirus pneumonia. | ||
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