Nanocrystalline graphite nanopore detection chip and preparation method and application thereof
The invention relates to a nanocrystalline graphite nanopore detection chip and a preparation method and application thereof, and belongs to the technical field of chip preparation. The nanocrystalline graphite nanopore detection chip takes a nanocrystalline graphite film with nanopores as a core; and due to easy-to-modify chemical characteristics of the surface of the nanocrystalline graphite film, higher resolution and sensitivity can be provided for nanopore sensing, so that in the process of detecting DNA, RNA, polypeptide or protein, a to-be-detected object is driven by an electric fieldto pass through nano-pores in the nano-crystalline graphite film in an electrolyte solution, and the purpose of detection is further achieved. The invention also provides the preparation method of thenanocrystalline graphite nanopore detection chip. The method comprises the following steps: processing the support substrate to form open pores, and preparing the nanocrystalline graphite film with the nanopores on the support substrate. The preparation method is simple and easy to operate..
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Patent| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Europäisches Patentamt - (2020) vom: 01. Dez. Zur Gesamtaufnahme - year:2020 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
WANG YUNJIAO [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2020-12-01, Last update posted on www.tib.eu: 2022-08-30, Last updated: 2023-02-09 |
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| Patentnummer: |
CN112014430 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA011445963 |
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| 520 | |a The invention relates to a nanocrystalline graphite nanopore detection chip and a preparation method and application thereof, and belongs to the technical field of chip preparation. The nanocrystalline graphite nanopore detection chip takes a nanocrystalline graphite film with nanopores as a core; and due to easy-to-modify chemical characteristics of the surface of the nanocrystalline graphite film, higher resolution and sensitivity can be provided for nanopore sensing, so that in the process of detecting DNA, RNA, polypeptide or protein, a to-be-detected object is driven by an electric fieldto pass through nano-pores in the nano-crystalline graphite film in an electrolyte solution, and the purpose of detection is further achieved. The invention also provides the preparation method of thenanocrystalline graphite nanopore detection chip. The method comprises the following steps: processing the support substrate to form open pores, and preparing the nanocrystalline graphite film with the nanopores on the support substrate. The preparation method is simple and easy to operate. | ||
| 650 | 4 | |a B82Y: Specific uses or applications of nanostructures; measurement or analysis of nanostructures; manufacture or treatment of nanostructures | |
| 650 | 4 | |a G01N: Investigating or analysing materials by determining their chemical or physical properties (measuring or testing processes other than immunoassay, involving enzymes or microorganisms c12m, c12q) | |
| 650 | 4 | |a bio | |
| 650 | 4 | |a C12Q: Measuring or testing processes involving enzymes, nucleic acids or microorganisms (immunoassay g01n0033530000); compositions or test papers therefor; processes of preparing such compositions; condition-responsive control in microbiological or enzymological processes | |
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| 700 | 0 | |a ZHOU DAMING |4 aut | |
| 700 | 0 | |a HE SHIXUAN |4 aut | |
| 700 | 0 | |a XIE WANYI |4 aut | |
| 700 | 0 | |a FANG SHAOXI |4 aut | |
| 700 | 0 | |a YIN BOHUA |4 aut | |
| 700 | 0 | |a SHI BIAO |4 aut | |
| 700 | 0 | |a TIAN RONG |4 aut | |
| 700 | 0 | |a YUAN JIAHU |4 aut | |
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