Low acidic species compositions and methods for producing and using the same using displacement chromatography
The present invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods for producing such low AR compositions using displacement chromatography. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNFα is detrimental, are also provided..
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Patent| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Europäisches Patentamt - (2017) vom: 27. Juni Zur Gesamtaufnahme - year:2017 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
WANG CHEN [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2017-06-27, Last update posted on www.tib.eu: 2022-06-11, Last updated: 2023-02-09 |
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| Patentnummer: |
US9688752 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA009124403 |
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| 245 | 1 | 0 | |a Low acidic species compositions and methods for producing and using the same using displacement chromatography |
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| 500 | |a Source: www.epo.org (no modifications made), First posted: 2017-06-27, Last update posted on www.tib.eu: 2022-06-11, Last updated: 2023-02-09 | ||
| 520 | |a The present invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods for producing such low AR compositions using displacement chromatography. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNFα is detrimental, are also provided. | ||
| 650 | 4 | |a che | |
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a C07K: Peptides (peptides containing β-lactam rings c07d;cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, c07d;ergot alkaloids of the cyclic peptide type c07d0519020000; single cell proteins, enzymes c12n;genetic engineering processes for obtaining peptides c12n0015000000) | |
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| 856 | 4 | 0 | |u https://worldwide.espacenet.com/patent/search/family/52826381/publication/US9688752A1?q=US9688752 |z kostenfrei |3 Volltext |
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