PREPARATION METHOD OF TABLET CONTAINING DAPAGLIFLOZIN ANSOLVATE AND TABLET CONTAINING DAPAGLIFLOZIN ANSOLVATE PREPARED BY THE SAME
The present invention relates to a method for preparing dapagliflozin nonsolvate-containing tablets, including: (A) a granule-forming step using a binding solvent, wherein a binder is allowed to be in contact with dapagliflozin nonsolvate, after the binder is dissolved or suspended in a binding solvent having a content of at least one alcohol selected from C2-C3 alcohols of 50 wt% or more, and carrying out molding and drying to form dry granules; and (B) a compressed product-forming step in which the dry granules are compressed with a disintegrating agent to form a compressed product. According to the present invention, it is possible to facilitate elution of dapagliflozin nonsolvate from the dapagliflozin nonsolvate-containing tablets, to control the elution pattern, and to control the dapagliflozin nonsolvate-containing tablets to have a uniform content. In addition, the dapagliflozin nonsolvate-containing tablets obtained by the method according to the present invention allows easy elution of dapagliflozin nonsolvate and is capable of controlling the elution pattern..
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Patent| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Europäisches Patentamt - (2020) vom: 29. Dez. Zur Gesamtaufnahme - year:2020 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
PARK BYOUNG WOO [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2020-12-29, Last update posted on www.tib.eu: 2022-05-30, Last updated: 2023-02-09 |
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| Patentnummer: |
KR20200144432 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA008312486 |
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| 245 | 1 | 0 | |a PREPARATION METHOD OF TABLET CONTAINING DAPAGLIFLOZIN ANSOLVATE AND TABLET CONTAINING DAPAGLIFLOZIN ANSOLVATE PREPARED BY THE SAME |
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| 520 | |a The present invention relates to a method for preparing dapagliflozin nonsolvate-containing tablets, including: (A) a granule-forming step using a binding solvent, wherein a binder is allowed to be in contact with dapagliflozin nonsolvate, after the binder is dissolved or suspended in a binding solvent having a content of at least one alcohol selected from C2-C3 alcohols of 50 wt% or more, and carrying out molding and drying to form dry granules; and (B) a compressed product-forming step in which the dry granules are compressed with a disintegrating agent to form a compressed product. According to the present invention, it is possible to facilitate elution of dapagliflozin nonsolvate from the dapagliflozin nonsolvate-containing tablets, to control the elution pattern, and to control the dapagliflozin nonsolvate-containing tablets to have a uniform content. In addition, the dapagliflozin nonsolvate-containing tablets obtained by the method according to the present invention allows easy elution of dapagliflozin nonsolvate and is capable of controlling the elution pattern. | ||
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| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
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