MULTI-EPITOPIC CONSTRUCT
To provide an effective treatment for atherosclerosis.SOLUTION: Provided are a recombinant construct and immunogenic and vaccine compositions each comprising (i) a scaffold portion, (ii) a first species of epitope capable of eliciting an anti-arteriosclerotic vascular disease response via a first pathway, and (iii) a second species of epitope capable of eliciting an anti-arteriosclerotic vascular disease via a second pathway that is independent from the first pathway. The epitope is associated with different pathways leading to atherosclerosis. In particular, such compositions elicit immune responses against antigens and pathogens involved in the development of atherosclerosis. Also provided are an inter alia method of treating and/or preventing the disease and a recombinant protein product.SELECTED DRAWING: None.
| Medienart: |
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Patent| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Europäisches Patentamt - (2021) vom: 18. Feb. Zur Gesamtaufnahme - year:2021 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
VIJAY KAKKAR [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2021-02-18, Last update posted on www.tib.eu: 2023-09-27, Last updated: 2023-10-06 |
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| Patentnummer: |
JP2021019614 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA007073739 |
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| 520 | |a To provide an effective treatment for atherosclerosis.SOLUTION: Provided are a recombinant construct and immunogenic and vaccine compositions each comprising (i) a scaffold portion, (ii) a first species of epitope capable of eliciting an anti-arteriosclerotic vascular disease response via a first pathway, and (iii) a second species of epitope capable of eliciting an anti-arteriosclerotic vascular disease via a second pathway that is independent from the first pathway. The epitope is associated with different pathways leading to atherosclerosis. In particular, such compositions elicit immune responses against antigens and pathogens involved in the development of atherosclerosis. Also provided are an inter alia method of treating and/or preventing the disease and a recombinant protein product.SELECTED DRAWING: None | ||
| 650 | 4 | |a C12N: Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media (microbiological testing media c12q0001000000) | |
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