NOVEL COMPOUND OF OHIONSIN F FOR PREVENTION AND TREATMENT OF ATHEROSCLEROSIS FROM POLYTRICHASTRUM ALPINUM
PURPOSE: A composition containing ohioensin F which is derived from Polytrichastrum alpinum for preventing or treating atherosclerosis is provided to suppress the expression of a cell adhesion molecule induced by TNF-alpha. CONSTITUTION: A pharmaceutical composition for preventing or treating artherosclerosis contains 0.01-10 wt% of ohioensin F denoted by chemical formula I, which is a benzonaphthoxanthenone-based compound, as an active ingredient. Ohioensin F suppresses the expression of a cell adhesion molecule induced by TNF-alpha. The cell adhesion molecule is ICAM-1 and VCAM-1..
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Patent| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Europäisches Patentamt - (2018) vom: 27. Sept. Zur Gesamtaufnahme - year:2018 |
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| Sprache: |
Unbestimmt |
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| Beteiligte Personen: |
YIM JOUNG HAN [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), Last update posted on www.epo.org: 2018-09-27, Last updated: 2021-03-11 |
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| Patentnummer: |
KR20130043415 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA006472311 |
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| 245 | 1 | 0 | |a NOVEL COMPOUND OF OHIONSIN F FOR PREVENTION AND TREATMENT OF ATHEROSCLEROSIS FROM POLYTRICHASTRUM ALPINUM |
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| 520 | |a PURPOSE: A composition containing ohioensin F which is derived from Polytrichastrum alpinum for preventing or treating atherosclerosis is provided to suppress the expression of a cell adhesion molecule induced by TNF-alpha. CONSTITUTION: A pharmaceutical composition for preventing or treating artherosclerosis contains 0.01-10 wt% of ohioensin F denoted by chemical formula I, which is a benzonaphthoxanthenone-based compound, as an active ingredient. Ohioensin F suppresses the expression of a cell adhesion molecule induced by TNF-alpha. The cell adhesion molecule is ICAM-1 and VCAM-1. | ||
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