Biological active polypeptide SKLVPVGYGIRKL as well as preparation method and application thereof
本发明涉及蛋白领域，具体涉及一种生物活性多肽SKLVPVGYGIRKL及其制备方法和应用，生物活性多肽SKLVPVGYGIRKL其氨基酸序列为Ser‑Lys‑Leu‑Val‑Pro‑Val‑Gly‑Tyr‑Gly‑Ile‑Arg‑Lys‑Leu。经过体外免疫功能调节实验、体外抗炎实验，验证了多肽SKLVPVGYGIRKL具有较好的免疫调节功能和抗炎活性；一方面，本发明的生物活性多肽SKLVPVGYGIRKL能够促进巨噬细胞体外增殖，提高机体抵御外界病原体感染的能力，降低机体发病率；另一方面，能够提高巨噬细胞一氧化氮诱生量增加的能力，提高机体抵御外界异物侵入，降低机体生病的机率，对开发具有免疫调节功能、抗炎功能的食品、保健品和药物具有十分重要的意义。.
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Patent| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Europäisches Patentamt - (2021) vom: 26. Juli Zur Gesamtaufnahme - year:2021 |
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| Sprache: |
Unbestimmt |
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| Beteiligte Personen: |
ZHANG SHAOHUI [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2019, Last update posted on www.epo.org: 2021-07-26, Last updated: 2021-07-27 |
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| Patentnummer: |
CN110938129 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA005890446 |
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| 520 | |a 本发明涉及蛋白领域，具体涉及一种生物活性多肽SKLVPVGYGIRKL及其制备方法和应用，生物活性多肽SKLVPVGYGIRKL其氨基酸序列为Ser‑Lys‑Leu‑Val‑Pro‑Val‑Gly‑Tyr‑Gly‑Ile‑Arg‑Lys‑Leu。经过体外免疫功能调节实验、体外抗炎实验，验证了多肽SKLVPVGYGIRKL具有较好的免疫调节功能和抗炎活性；一方面，本发明的生物活性多肽SKLVPVGYGIRKL能够促进巨噬细胞体外增殖，提高机体抵御外界病原体感染的能力，降低机体发病率；另一方面，能够提高巨噬细胞一氧化氮诱生量增加的能力，提高机体抵御外界异物侵入，降低机体生病的机率，对开发具有免疫调节功能、抗炎功能的食品、保健品和药物具有十分重要的意义。 | ||
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