Parathyroid hormone 1-34 nasal spray as well as preparation method and application thereof
The invention relates to a parathyroid hormone 1-34 pharmaceutical composition and a preparation method thereof. Specifically, the invention relates to a parathyroid hormone 1-34 pharmaceutical composition, which contains parathyroid hormone 1-34 as an active ingredient and a pharmaceutically acceptable carrier, and the carrier at least comprises a buffer solution, a penetration enhancer, a stabilizer and a preservative. The parathyroid hormone 1-34 pharmaceutical composition is a parathyroid hormone 1-34 nasal spray or a nasal spray combination. The parathyroid hormone 1-34 nasal spray or thenasal spray combination prepared by the method has the advantages that the first-pass effect is avoided, and the bioavailability is high; the effect taking is fast; the administration is convenient,the patient compliance is strong, the nasal spray is subjected to nasal mucosa absorption in the use process, and can be used for favorably reducing the pain of injection administration of polypeptidedrugs and the like..
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Patent| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Europäisches Patentamt - (2021) vom: 31. Mai Zur Gesamtaufnahme - year:2021 |
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| Sprache: |
Unbestimmt |
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| Beteiligte Personen: |
ZHENG AIPING [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
615 |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2019, Last update posted on www.epo.org: 2021-05-31, Last updated: 2021-06-21 |
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| Patentnummer: |
CN110755380 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA004988949 |
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| 500 | |a Source: www.epo.org (no modifications made), First posted: 2019, Last update posted on www.epo.org: 2021-05-31, Last updated: 2021-06-21 | ||
| 520 | |a The invention relates to a parathyroid hormone 1-34 pharmaceutical composition and a preparation method thereof. Specifically, the invention relates to a parathyroid hormone 1-34 pharmaceutical composition, which contains parathyroid hormone 1-34 as an active ingredient and a pharmaceutically acceptable carrier, and the carrier at least comprises a buffer solution, a penetration enhancer, a stabilizer and a preservative. The parathyroid hormone 1-34 pharmaceutical composition is a parathyroid hormone 1-34 nasal spray or a nasal spray combination. The parathyroid hormone 1-34 nasal spray or thenasal spray combination prepared by the method has the advantages that the first-pass effect is avoided, and the bioavailability is high; the effect taking is fast; the administration is convenient,the patient compliance is strong, the nasal spray is subjected to nasal mucosa absorption in the use process, and can be used for favorably reducing the pain of injection administration of polypeptidedrugs and the like. | ||
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