RETROVIRAL VECTORS CONTAINING A REVERSE ORIENTATION HUMAN UBIQUITIN C PROMOTER
In certain embodiments a recombinant retroviral vector is provided where the vector comprises a human ubiquitin C (UBC) promoter operably linked to a transgene where the promoter and the transgene are in a reverse orientation so that the direction of transcription of the transgene from the promoter is oriented towards a 5′ long terminal repeat (LTR) of the vector..
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Patent| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Europäisches Patentamt - (2021) vom: 27. Juli Zur Gesamtaufnahme - year:2021 |
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| Sprache: |
Unbestimmt |
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| Beteiligte Personen: |
KOHN DONALD B [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2015, Last update posted on www.epo.org: 2021-07-27, Last updated: 2021-07-27 |
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| Patentnummer: |
EP3317416 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA004428145 |
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| 245 | 1 | 0 | |a RETROVIRAL VECTORS CONTAINING A REVERSE ORIENTATION HUMAN UBIQUITIN C PROMOTER |
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| 520 | |a In certain embodiments a recombinant retroviral vector is provided where the vector comprises a human ubiquitin C (UBC) promoter operably linked to a transgene where the promoter and the transgene are in a reverse orientation so that the direction of transcription of the transgene from the promoter is oriented towards a 5′ long terminal repeat (LTR) of the vector. | ||
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