Application of reagent for promoting DOCK11 expression as medicine for treating neuropathic pain
The invention discloses application of a reagent for promoting DOCK11 expression as a medicine for treating neuropathic pain. The research finds that mice suffering from neuropathic pain have obvious mechanical abnormal pain and thermal hyperalgesia, and expression of DOCK11 is closely related to mechanical pain and thermal pain of CCI mice. The overexpressed DOCK11 vector can effectively promote the expression of DOCK11 in the spinal cord and obviously inhibit neuropathic pain at the same time. The research results of the invention provide potential therapeutic targets for clinical treatment of neuropathic pain..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 10. Nov. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
LI JING [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-11-10, Last update posted on www.tib.eu: 2024-04-22, Last updated: 2024-04-26 |
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| Patentnummer: |
CN117018197 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA003934179 |
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| 520 | |a The invention discloses application of a reagent for promoting DOCK11 expression as a medicine for treating neuropathic pain. The research finds that mice suffering from neuropathic pain have obvious mechanical abnormal pain and thermal hyperalgesia, and expression of DOCK11 is closely related to mechanical pain and thermal pain of CCI mice. The overexpressed DOCK11 vector can effectively promote the expression of DOCK11 in the spinal cord and obviously inhibit neuropathic pain at the same time. The research results of the invention provide potential therapeutic targets for clinical treatment of neuropathic pain. | ||
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