Pigeon source gene VI type Newcastle disease virus mGZ08, application, preparation method, culture method and vaccine
The invention relates to the technical field of vaccine production, and discloses a pigeon-derived gene VI type Newcastle disease virus mGZ08 with the preservation number of CCTCC (China Center For Type Culture Collection) NO: V202253. The preservation date is July 5, 2022; the pigeon-derived gene VI-type Newcastle disease virus mGZ08 is preserved in China Center for Type Culture Collection, and meanwhile, the invention also provides a preparation method of the pigeon-derived gene VI-type Newcastle disease virus mGZ08, and the method does not cause random homologous recombination of virus genes and can accurately obtain a target genotype; moreover, a series of optimization is carried out on culture conditions during culture, so that the virus titer is further improved; finally, experiments prove that the inactivated vaccine prepared from the pigeon source gene VI type Newcastle disease virus mGZ08 provided by the invention has a more excellent protection rate compared with the traditional chicken Newcastle disease vaccine in the market..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 24. Okt. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
REN TAO [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-10-24, Last update posted on www.tib.eu: 2024-04-22, Last updated: 2024-04-26 |
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| Patentnummer: |
CN116926022 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA003840190 |
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| 520 | |a The invention relates to the technical field of vaccine production, and discloses a pigeon-derived gene VI type Newcastle disease virus mGZ08 with the preservation number of CCTCC (China Center For Type Culture Collection) NO: V202253. The preservation date is July 5, 2022; the pigeon-derived gene VI-type Newcastle disease virus mGZ08 is preserved in China Center for Type Culture Collection, and meanwhile, the invention also provides a preparation method of the pigeon-derived gene VI-type Newcastle disease virus mGZ08, and the method does not cause random homologous recombination of virus genes and can accurately obtain a target genotype; moreover, a series of optimization is carried out on culture conditions during culture, so that the virus titer is further improved; finally, experiments prove that the inactivated vaccine prepared from the pigeon source gene VI type Newcastle disease virus mGZ08 provided by the invention has a more excellent protection rate compared with the traditional chicken Newcastle disease vaccine in the market. | ||
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