Magnetic drug-loadable blocking hydrogel as well as preparation method and application thereof
The invention relates to the technical field of medical preparations, in particular to magnetic drug-loadable blocking hydrogel and a preparation method and application thereof.The magnetic drug-loadable blocking hydrogel is formed by in-situ cross-linking of a drug-loading precursor solution and a cross-linking agent solution, and preparation raw materials of the drug-loading precursor solution at least comprise a polyethylene glycol derivative, magnetic particles, a drug-loading solution and a first buffer solution, by optimizing the bi-component hydrogel system, the provided product has excellent injectability, formability, mechanical property, biocompatibility and postoperative removability, and meanwhile, the preparation method is simple and convenient to operate, and has great industrialization value and clinical use value..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 31. Okt. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
WANG CHURONG [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-10-31, Last update posted on www.tib.eu: 2024-04-22, Last updated: 2024-04-26 |
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| Patentnummer: |
CN116966136 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA003765717 |
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| 520 | |a The invention relates to the technical field of medical preparations, in particular to magnetic drug-loadable blocking hydrogel and a preparation method and application thereof.The magnetic drug-loadable blocking hydrogel is formed by in-situ cross-linking of a drug-loading precursor solution and a cross-linking agent solution, and preparation raw materials of the drug-loading precursor solution at least comprise a polyethylene glycol derivative, magnetic particles, a drug-loading solution and a first buffer solution, by optimizing the bi-component hydrogel system, the provided product has excellent injectability, formability, mechanical property, biocompatibility and postoperative removability, and meanwhile, the preparation method is simple and convenient to operate, and has great industrialization value and clinical use value. | ||
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a A61L: Methods or apparatus for sterilising materials or objects in general; disinfection, sterilisation, or deodorisation of air; chemical aspects of bandages, dressings, absorbent pads, or surgical articles; materials for bandages, dressings, absorbent pads, or surgical articles (preservation of bodies or disinfecting characterised by the agent employed a01n;preserving, e.g. sterilising, food or foodstuffs a23;preparations for medical, dental or toilet purposes a61k) | |
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
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