COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL DISEASES
The invention described herein provides methods and compositions for treating certain diseases, using a composition for regulating a primate PTBP gene expression comprising a Cas effector protein and a guide RNA (gRNA) to target a target sequence or its complement of the primate PTBP gene or a transcript thereof, which suppresses the expression of the primate PTBP gene..
| Medienart: |
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 28. Dez. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
ZHOU HAIBO [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-12-28, Last update posted on www.tib.eu: 2024-04-03, Last updated: 2024-04-09 |
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| Patentnummer: |
WO2023245670 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA00311807X |
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| 520 | |a The invention described herein provides methods and compositions for treating certain diseases, using a composition for regulating a primate PTBP gene expression comprising a Cas effector protein and a guide RNA (gRNA) to target a target sequence or its complement of the primate PTBP gene or a transcript thereof, which suppresses the expression of the primate PTBP gene. | ||
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| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
| 650 | 4 | |a C12N: Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media (microbiological testing media c12q0001000000) | |
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