INTRAVASCULAR DELIVERY OF NANOPARTICLE COMPOSITIONS AND USES THEREOF
The present invention provides methods of delivering a composition comprising nanoparticles that comprise a macrolide and an albumin by directly injecting the nanoparticle composition into the blood vessel wall or the tissue surrounding the blood vessel wall. The methods can be used for inhibiting negative remodeling or vascular fibrosis in the blood vessel and are useful for treating various diseases.
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Patent| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Europäisches Patentamt - (2020) vom: 14. Jan. Zur Gesamtaufnahme - year:2020 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
SEWARD KIRK [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2020-01-14, Last update posted on www.tib.eu: 2024-04-01, Last updated: 2024-04-09 |
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| Patentnummer: |
CA2834040 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA002899205 |
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| 520 | |a The present invention provides methods of delivering a composition comprising nanoparticles that comprise a macrolide and an albumin by directly injecting the nanoparticle composition into the blood vessel wall or the tissue surrounding the blood vessel wall. The methods can be used for inhibiting negative remodeling or vascular fibrosis in the blood vessel and are useful for treating various diseases | ||
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
| 650 | 4 | |a A61M: Devices for introducing media into, or onto, the body (introducing media into or onto the bodies of animals a61d0007000000; means for inserting tampons a61f0013260000; devices for administering food or medicines orally a61j; containers for collecting, storing or administering blood or medical fluids a61j0001050000); devices for transducing body media or for taking media from the body (surgery a61b; chemical aspects of surgical articles a61l; magnetotherapy using magnetic elements placed within the body a61n0002100000); devices for producing or ending sleep or stupor | |
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