-Tie2 A Novel anti-Tie2 antibody or its antigen-binding fragments and the use thereof
The present invention relates to novel anti-Tie2 antibodies or antigen-binding fragments thereof, and uses thereof. The antibodies or antigen-binding fragments thereof include at least one heavy chain variable region including CDR1-H having an amino acid sequence of X1-X2-X3-X4-X5-X6-Y-X7-M-H-W-X8; and at least one light chain variable region including CDR1-L having an amino acid sequence of X17-X18-X19-X20-X21-X22-X23-N-X24-X25-X26-Y. The antibody or antigen-binding fragment thereof is applied as an active ingredient of a pharmaceutical composition for humans without concern for rejection reaction..
| Medienart: |
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Patent| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Europäisches Patentamt - (2022) vom: 10. Mai Zur Gesamtaufnahme - year:2022 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
JEONG KI MIN [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2022-05-10, Last update posted on www.tib.eu: 2024-04-03, Last updated: 2024-04-09 |
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| Patentnummer: |
KR20220059924 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA002887916 |
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| 520 | |a The present invention relates to novel anti-Tie2 antibodies or antigen-binding fragments thereof, and uses thereof. The antibodies or antigen-binding fragments thereof include at least one heavy chain variable region including CDR1-H having an amino acid sequence of X1-X2-X3-X4-X5-X6-Y-X7-M-H-W-X8; and at least one light chain variable region including CDR1-L having an amino acid sequence of X17-X18-X19-X20-X21-X22-X23-N-X24-X25-X26-Y. The antibody or antigen-binding fragment thereof is applied as an active ingredient of a pharmaceutical composition for humans without concern for rejection reaction. | ||
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