Medicine for treating advanced tumor and fibrosis diseases
The invention provides a medicine for treating advanced tumor and fibrosis diseases, and belongs to the field of biological medicine. The medicine is a preparation prepared by taking the humanized nano antibody disclosed by the invention as an active ingredient and adding auxiliary materials acceptable in science. The humanized nano antibody can block the combination of TGF beta and a receptor thereof while keeping affinity with TGF beta, reduces immune risks caused by heterology to the greatest extent, is more beneficial to penetrating through a blood-brain barrier, can reach the interior of a tumor more easily to play a treatment effect, and can be used for preparing a medicine for treating tumors. The compound has a wide application prospect in preparation of medicines for treating advanced tumors and fibrosis diseases..
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Patent| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Europäisches Patentamt - (2024) vom: 26. Jan. Zur Gesamtaufnahme - year:2024 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
YU DING [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2024-01-26, Last update posted on www.tib.eu: 2024-03-25, Last updated: 2024-03-29 |
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| Patentnummer: |
CN117448338 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA002724774 |
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| 245 | 1 | 0 | |a Medicine for treating advanced tumor and fibrosis diseases |
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| 520 | |a The invention provides a medicine for treating advanced tumor and fibrosis diseases, and belongs to the field of biological medicine. The medicine is a preparation prepared by taking the humanized nano antibody disclosed by the invention as an active ingredient and adding auxiliary materials acceptable in science. The humanized nano antibody can block the combination of TGF beta and a receptor thereof while keeping affinity with TGF beta, reduces immune risks caused by heterology to the greatest extent, is more beneficial to penetrating through a blood-brain barrier, can reach the interior of a tumor more easily to play a treatment effect, and can be used for preparing a medicine for treating tumors. The compound has a wide application prospect in preparation of medicines for treating advanced tumors and fibrosis diseases. | ||
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| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a C12N: Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media (microbiological testing media c12q0001000000) | |
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
| 650 | 4 | |a C07K: Peptides (peptides containing β-lactam rings c07d;cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, c07d;ergot alkaloids of the cyclic peptide type c07d0519020000; single cell proteins, enzymes c12n;genetic engineering processes for obtaining peptides c12n0015000000) | |
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