Preparation and test method of BJZS001 for inhibiting cavernous smooth muscle apoptosis caused by hyperglycemia
The invention discloses a preparation and inspection method of BJZS001 for inhibiting cavernosum smooth muscle apoptosis caused by hyperglycemia, which comprises the following steps: step 1, health inspection of a donor: the donor accepts strict prenatal examination and medical history investigation, and signs an informed agreement; step 2, preparing raw materials: preparing the hUCMSC by using a commercial serum-free and animal-source-component-free culture system, and strictly verifying all auxiliary materials and consumables for later use after being prepared; 3, conveying the umbilical cord: collecting the umbilical cord after delivery of the baby, and delivering the umbilical cord to a laboratory through cold chain transportation; according to the method, BJZS001 is transplanted through cavernous bodies, rat cavernous body smooth muscle apoptosis caused by hyperglycemia can be effectively inhibited, continuous hyperglycemia rat cavernous body smooth muscle loss can be reduced, the potential of inducing regeneration and repair of cavernous body smooth muscles is achieved, and the method has the advantages of being capable of effectively inhibiting hyperglycemia of the rat cavernous body smooth muscle apoptosis and reducing hyperglycemia of the rat cavernous body smooth muscle apoptosis and reducing hyperglycemia of the rat cavernous body smooth muscle apoptosis. Therefore, the BJZS001 has a great prospect in the aspect of developing intervention or therapeutic drugs for smooth muscle loss caused by hyperglycemia..
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Patent| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Europäisches Patentamt - (2024) vom: 16. Jan. Zur Gesamtaufnahme - year:2024 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
YUAN CHUNHUI [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2024-01-16, Last update posted on www.tib.eu: 2024-03-25, Last updated: 2024-03-29 |
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| Patentnummer: |
CN117398411 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA002659492 |
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| 245 | 1 | 0 | |a Preparation and test method of BJZS001 for inhibiting cavernous smooth muscle apoptosis caused by hyperglycemia |
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| 500 | |a Source: www.epo.org (no modifications made), First posted: 2024-01-16, Last update posted on www.tib.eu: 2024-03-25, Last updated: 2024-03-29 | ||
| 520 | |a The invention discloses a preparation and inspection method of BJZS001 for inhibiting cavernosum smooth muscle apoptosis caused by hyperglycemia, which comprises the following steps: step 1, health inspection of a donor: the donor accepts strict prenatal examination and medical history investigation, and signs an informed agreement; step 2, preparing raw materials: preparing the hUCMSC by using a commercial serum-free and animal-source-component-free culture system, and strictly verifying all auxiliary materials and consumables for later use after being prepared; 3, conveying the umbilical cord: collecting the umbilical cord after delivery of the baby, and delivering the umbilical cord to a laboratory through cold chain transportation; according to the method, BJZS001 is transplanted through cavernous bodies, rat cavernous body smooth muscle apoptosis caused by hyperglycemia can be effectively inhibited, continuous hyperglycemia rat cavernous body smooth muscle loss can be reduced, the potential of inducing regeneration and repair of cavernous body smooth muscles is achieved, and the method has the advantages of being capable of effectively inhibiting hyperglycemia of the rat cavernous body smooth muscle apoptosis and reducing hyperglycemia of the rat cavernous body smooth muscle apoptosis and reducing hyperglycemia of the rat cavernous body smooth muscle apoptosis. Therefore, the BJZS001 has a great prospect in the aspect of developing intervention or therapeutic drugs for smooth muscle loss caused by hyperglycemia. | ||
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| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a G01N: Investigating or analysing materials by determining their chemical or physical properties (measuring or testing processes other than immunoassay, involving enzymes or microorganisms c12m, c12q) | |
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
| 650 | 4 | |a C12N: Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media (microbiological testing media c12q0001000000) | |
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