Alkyl-substituted alpha-carboline analogue or pharmaceutical salt thereof, pharmaceutical composition thereof, and preparation method and application of alkyl-substituted alpha-carboline analogue or pharmaceutical salt thereof
The invention discloses a hydrocarbyl-substituted alpha-carboline analogue or a pharmaceutical salt thereof and a pharmaceutical composition thereof, which not only have anti-neuritis activity, but also can effectively protect nerve cells from being influenced by oxidative stress, can be used for preventing and/or treating diseases, and can be used for preventing and/or treating diseases. The diseases comprise neurodegenerative diseases (such as Alzheimer's disease), neuritis diseases (such as cranial neuritis) and the like, and the defect that current cholinergic drugs can only relieve symptoms of the neurodegenerative diseases (such as Alzheimer's disease) can be overcome..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 06. Juni Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
DAN WENJIA [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-06-06, Last update posted on www.tib.eu: 2023-09-26, Last updated: 2023-09-29 |
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| Patentnummer: |
CN116217567 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA002420074 |
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| 245 | 1 | 0 | |a Alkyl-substituted alpha-carboline analogue or pharmaceutical salt thereof, pharmaceutical composition thereof, and preparation method and application of alkyl-substituted alpha-carboline analogue or pharmaceutical salt thereof |
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| 520 | |a The invention discloses a hydrocarbyl-substituted alpha-carboline analogue or a pharmaceutical salt thereof and a pharmaceutical composition thereof, which not only have anti-neuritis activity, but also can effectively protect nerve cells from being influenced by oxidative stress, can be used for preventing and/or treating diseases, and can be used for preventing and/or treating diseases. The diseases comprise neurodegenerative diseases (such as Alzheimer's disease), neuritis diseases (such as cranial neuritis) and the like, and the defect that current cholinergic drugs can only relieve symptoms of the neurodegenerative diseases (such as Alzheimer's disease) can be overcome. | ||
| 650 | 4 | |a C07D: Heterocyclic compounds (macromolecular compounds c08) | |
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
| 650 | 4 | |a che | |
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
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